No increased risk of infant hypospadias after maternal use of loratadine in early pregnancy

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No increased risk of infant hypospadias after maternal use of loratadine in early pregnancy

The original report published in 2001 on a possible association between maternal use of loratadine and an increased risk of infant hypospadias, based on data in the Swedish Medical Birth Register 1995-2001, has been followed up by continued surveillance in the same register. The original "signal" was based on 15 infants with hypospadias among 2780 loratadine-exposed infants born, representing a...

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Maternal use of Loratadine during pregnancy and risk of hypospadias in offspring

To examine the risk of hypospadias after exposure to loratadine and other antihistamines during pregnancy, we conducted a population-based case-control study in four Danish counties, which account for 30% of the Danish population (approximately 1.6 M). We obtained data on maternal use of antihistamines from prescription databases, and data on birth outcomes from the Danish Medical Birth Registr...

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Effect of early urethral dilatation in prevention of complications in hypospadias patients after urethroplasty

Introduction: Hypospadias is a common congenital malformation in boys. One of the common surgical techniques for correction of hypospadias is (Tubularized Incised Plate urethraplasty=TIP). Meatal stenosis and fistula formation are known post-operative complications. The purpose of our study was to evaluate the effect of early urethral dilatation in prevention of post operative complications. Me...

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Use of clomifene during early pregnancy and risk of hypospadias: population based case-control study.

Contributors: The study idea originated from SP and was further developed in discussions with TT and specified in communication with all authors. All authors agreed on the study design and are guarantors for data from their country: AF for data from Italy, LH for Sweden, RK for Germany, FT-G for Spain, DW for the Netherlands, and SP for the United Kingdom. AB coordinated the data collection.Dat...

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Risk factors assoicated with increased the chance of ectopic pregnancy

Introduction: Ectopic Pregnancy (EP) is one of the most common causes of maternal mortality. The aim of this study was to evaluate the risk factors that increase the chances of ectopic pregnancy. Materials and Methods: This case-control study was performed in the hospitals of Shahroud University of Medical Sciences in 2018 by census method. Pregnant women who were hospitalized with suspected ec...

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ژورنال

عنوان ژورنال: International Journal of Medical Sciences

سال: 2006

ISSN: 1449-1907

DOI: 10.7150/ijms.3.106